Meta-analysis of randomised controlled trials of the effectiveness of antiarrhythmic agents at promoting sinus rhythm in patients with atrial fibrillation (Structured abstract)
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چکیده
Meta-analysis of randomised controlled trials of the effectiveness of antiarrhythmic agents at promoting sinus rhythm in patients with atrial fibrillation (Structured abstract) • Authors' objectives • Searching • Study selection: study designs • Study selection: specific interventions • Study selection: participants • Study selection: outcomes • Study selection: how were decisions on the relevance of primary studies made? • Validity assessment • Data extraction • Methods of synthesis: how were the studies combined? • Methods of synthesis: how were differences between studies investigated? • Results of the review • Authors' conclusions • CRD commentary • Implications of the review for practice and research • Funding • URL for original research • Record status • CRD database number • Index terms Export Citation Meta-analysis of randomised controlled trials of the effectiveness of antiarrhythmic agents at promoting sinus rhythm in patients with atrial fibrillation (Structured abstract)
منابع مشابه
Meta-analysis of randomised controlled trials of the effectiveness of antiarrhythmic agents at promoting sinus rhythm in patients with atrial fibrillation.
OBJECTIVE To conduct a meta-analysis of randomised controlled trials to estimate the effectiveness of antiarrhythmic drugs at promoting sinus rhythm in patients with atrial fibrillation. DESIGN Articles were identified by using a comprehensive search of English language papers indexed in Medline from 1966 to August 2001. For the outcomes of sinus rhythm and death, a random effects model was u...
متن کاملCARDIOVASCULAR MEDICINE Meta-analysis of randomised controlled trials of the effectiveness of antiarrhythmic agents at promoting sinus rhythm in patients with atrial fibrillation
ed from these articles. There were 43, 29, 47, 1, 51, 21, and 12 trials for placebo, class IA, IC, II, III or IV drugs, and digoxin, respectively. Some trials evaluated more than two drugs or evaluated combinations of drugs. These articles described trials that were conducted in 24 countries and published between 1970 and 2001. The total number of enrolled patients was 8563 (range 18–506). The ...
متن کاملRate vs rhythm control in patients with atrial fibrillation: a meta-analysis.
BACKGROUND The 2 fundamental approaches to the management of atrial fibrillation (AF) are reestablishing and maintaining sinus rhythm (rhythm control) and controlling ventricular rate with atrioventricular node blocking agents (rate control). We performed a meta-analysis of randomized controlled trials comparing these strategies in patients with AF to add precision to the relative merits of bot...
متن کاملEfficacy and safety of quinidine therapy for maintenance of sinus rhythm after cardioversion. A meta-analysis of randomized control trials.
Because individual studies evaluating the role of quinidine in the maintenance of sinus rhythm after cardioversion from chronic atrial fibrillation have involved relatively few patients, a meta-analysis of randomized control trials was performed. Six trials published between 1970 and 1984 were selected by two blinded reviewers based on study design and statistical analysis. Data from these six ...
متن کاملClinical effectiveness of antiarrhythmic treatment after electrical cardioversion in patients without structural heart disease.
INTRODUCTION AND OBJECTIVES The aim was to investigate the clinical effectiveness of using antiarrhythmic drugs after electrical cardioversion in patients without structural heart disease, including their effect on the maintenance of sinus rhythm. METHODS In total, 528 patients with persistent atrial fibrillation but without significant structural heart disease who underwent successful electr...
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